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The safety and scientific validity of this study is the responsibility of the study sponsor and investigators. This is an efficacy trial to understand the right dosage of Abobotulinum toxin A which can be affective.Listing a study does not mean it has been evaluated by the U. The study will involve an injection of 2.5 units of Dysport on each side of the affected vocal cords for patients with a diagnosis of Primary Tourette's syndrome.For unknown reasons, males are more likely to be affected than females - while Tourette's often runs in families.In cases where tics are more frequent or severe, medication such as such as alpha2-adrenergic agonists, muscle relaxants and dopamine antagonists can help to reduce them.Tourette’s is far more common that most people realise – affecting around one in every 100 people.Tourette’s is a neurological condition which affects the brain and nervous system, and is characterised by involuntary movements and noises called tics.It is often associated with outbursts of swearing and other rude language, but this is just one element of the condition - which not everyone has.

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DESPITE being a recognised neurological condition, there's still an element of taboo surrounding Tourette's.Physical: Jerking the head, or jumping up and down Tics can also be either simple (small movements or uttering a single sound) or complex (a series of movements/phrases).Most people who have been diagnosed with Tourette's have a combination of physical and vocal tics. Our intervention will be the injection of Abobotulinum toxin A into the affected site/vocal cords for patients with the diagnosis of Primary Tourette's syndrome.

The patients will also complete a self assessment survey on how vocal tics affect their daily lives.

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